A new 37 000 adolescents follow-up study of 17 year old year Israelis concluded that the risk of diabetes is primarily associated with increased BMI (BMI) of diagnosis in young adulthood, while the risk of coronary heart disease is associated with a BMI in adolescence and adulthood.
The results are published in the April 7 Edition, the New England Journal of Medicine.
Author of the study, Amir Tirosh, MD PhD, of the Division of the endocrine system Brigham and women's hospital said: "the study suggests that the problem of obesity in children and adolescents is probably only the tip of the iceberg of an increased risk of diabetes type 2 and heart disease in adulthood."
The research team, which also includes professors Iris Shai and Assaf Rudich, of Ben-Gurion University in Beer-Sheva, Israel, as well as researchers in the medical corps of the forces of IDF (IDF) and Tel Hashomer, was followed by 37 000 members of staff at the career of the army israélienneà starting from the age of 17.
Their body mass index was recorded in the base line and once again every several years. In a follow-up in the average of 17 years, the average body mass index participants has increased at a rate of 0, 2-0, 3 units per year, with an average weight of mounting earn about 30 books between 17 and 30 years. During the study period, 1 173 new cases of diabetes and 327 new cases of heart disease was diagnosed.
Controlling multiple risk factors for the two diseases, including age, blood glucose fasting, lipids in the blood, blood pressure, family history and smoking, researchers have discovered that in 17 years, BMI, even in the normal range currently considerably predict the appearance of these two diseases. Each increase of 1 unit of BMI was associated with an approximately 10% of higher risk for diabetes type 2 to young adults and an increase of 12% of the risk of heart disease.
"Previous studies do step unequivocally confirmed the association between the disease and BMI from pre-adulthood into young adulthood." This study is important because it demonstrates that the association exists in normal values in currently considered BMI, a different effect on the two diseases that occur in the young adult age and an age group that is often overlooked"said Professor Assaf Rudich.
In particular, the risk at the age of 17 years was significant at a BMI of 23.4 Kg/m2 or higher for the diabetes and 20.9 Kg/m2 or higher for diseases of the heart (these values correspond to a weight of 163 books or books 146 in an adolescent male 5'10 "respectively"). For diabetes, BMI years risk predicted 17 mainly because it is associated with BMI later in life. However, for heart disease, two BMI in adolescence, as in the adult body mass index independently predicts the risk of the disease.
"It appears that cardiac disease is more memoriable. BMI of diabetes, and history of BMI for an individual must be part of the risk assessment,", said Professor Iris Shai. "We have options, not necessarily pharmacological, to provide to patients to reduce the risk of heart disease." "Recent intervention trials demonstrated that the change of consumer habits can stop not only the progression of the atheorsclerosis, the underlying process of heart disease, but it could also reverse it."
Dr. Amir Tirosh adds, "for the prevention of early-onset of diseases of the heart in adulthood, it would seem that early intervention is necessary to promote healthy lifestyles, even during childhood."
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